Discoverative AI for Neuroscience
Hosted at AIAS+ Chen Institute Symposium for AI Advancing Science and Society
AIAS+ 2026 Symposium · Workshop W02 · San Francisco

Discoverative AI
for Neuroscience

Toward AI systems that form hypotheses, design experiments, and refine their own understanding of neural systems.

Friday, November 6, 2026 San Francisco, CA Two workshop sessions
Organized by
About the workshop

A new phase in the dialogue between AI and the brain.

AI and neuroscience have long evolved in tandem — early AI drew inspiration from the brain, and modern AI has now reached a capability that can fundamentally reshape how neuroscience is done.

This workshop explores a phase in which AI moves beyond data analysis and modeling to become an active participant in scientific discovery. We take inspiration from the history of neuroscience — how transformative ideas about the brain were conceived, tested, and refined — and build toward a more ambitious question:

Can AI systems learn to generate and pursue scientific insight at superhuman scale?

We envision discoverative AI systems that do not merely process data, but continuously formulate hypotheses, design experiments, generate data, and iteratively refine their understanding of neural systems — shifting from stochastic, human-expert-limited hypothesis generation to expansive, automated exploration of the brain's complexity.

How this differs from brain-inspired AI

Where NeuroAI efforts (e.g. at CSHL and NIH) build next-generation AI inspired by the brain, this workshop emphasizes the reverse direction: leveraging modern AI to advance neuroscience itself — systems that generate hypotheses, design experiments, and participate in iterative scientific discovery.

Themes & topics

What we'll explore

The workshop explores methods and questions that move neuroscience from prediction and pattern-recognition toward mechanistic understanding.

01

Neural & behavioral data

AI methods for modeling and interpreting complex, high-dimensional neural and behavioral recordings.

02

Hypothesis generation

Scientific reasoning and automated hypothesis generation about how neural systems work.

03

Closed-loop experiments

AI-driven experimental design, active learning, and closed-loop neuroscience.

04

Causal & mechanistic

Causal inference and mechanistic models that move past correlation toward how the brain computes.

05

Foundation models

Multimodal and foundation models trained across diverse brain and behavior datasets.

06

Brain-inspired memory

Brain-inspired and memory-centric AI architectures.

07

Scientific agents

Agents that plan, reason, and act within iterative discovery workflows.

08

Benchmarks & eval

Datasets, simulation environments, and evaluation frameworks for discoverative systems.

Invited experts

Meet the researchers shaping the conversation

Our invited experts bring perspectives spanning neuroscience, artificial intelligence, research strategy, and scientific innovation.

Speakers

30-minute talk + 5-minute Q&A

  • Dong Song
  • Yan Liu
  • Shaul Druckmann
  • Joseph Monaco
  • Wei Wang

Panelists

Audience questions and direct discussion

  • Charles Ng
  • Joseph Monaco
  • Lu Chen
  • Shaul Druckmann
  • Yan Liu
Dong Song

Dong Song

University of Southern California
ModeratorSpeaker

Dong Song is an associate professor of neurological surgery and biomedical engineering at USC and director of the Neural Modeling and Interface Laboratory. His research combines computational neuroscience, nonlinear dynamical modeling, and neural-interface technologies to understand learning and memory in the hippocampus. A major focus of his work is developing biologically interpretable brain models and biomimetic neural prostheses that can restore or enhance cognitive functions impaired by neurological disease or injury.

Shaul Druckmann

Shaul Druckmann

Stanford University
SpeakerPanelist

Shaul Druckmann is an associate professor of neurobiology and psychiatry and behavioral sciences at Stanford University. His laboratory combines neural-population recordings, mathematical theory, and circuit analysis to understand how brain networks represent information and perform computations. His research on distributed and resilient memory systems offers biological principles for developing more robust and interpretable AI.

Joseph Monaco

Joseph Monaco

NIH / NINDS
SpeakerPanelist

Joseph Monaco is a scientific program manager in the Office of the BRAIN Director at NIH/NINDS, where he helps shape and advance NeuroAI research. He has played an active role in organizing NIH BRAIN NeuroAI workshops, building connections between the neuroscience and AI communities, and identifying opportunities for transformative research at their intersection. A computational neuroscientist by training, his work explores how neural dynamics underlying memory, navigation, and embodied behavior can inspire more adaptive, flexible, and biologically grounded AI systems.

Yan Liu

Yan Liu

University of Southern California
SpeakerPanelist

Yan Liu is the Fletcher Jones Foundation Chair in Computer Science and a professor of computer science, electrical and computer engineering, and biomedical sciences at USC. Her research focuses on machine learning and artificial intelligence, particularly time-series modeling, explainable AI, and efficient optimization, with applications in healthcare, sustainability, and social systems. She also directs USC’s Center for Machine Learning and co-chairs the Institute of Ethics and Trust in Computing.

Wei Wang

Wei Wang

University of California, Los Angeles
Speaker

Wei Wang is the Leonard Kleinrock Chair Professor of Computer Science and Computational Medicine at UCLA and director of the Scalable Analytics Institute. Her research develops machine-learning and data-mining methods for large, complex biomedical datasets, including work in causal discovery and computer-assisted experiment planning. Her work demonstrates how AI can move beyond recognizing patterns to help scientists generate hypotheses and design more informative experiments.

Charles “Chuck” Ng

Charles “Chuck” Ng

Foundation for Science & AI Research
Panelist

Charles “Chuck” Ng is an entrepreneur and technology investor who co-founded Eureka Therapeutics and has invested in or advised companies including Databricks, Ironclad, Mammoth Biosciences, Meta, and Alibaba. As co-founder of the Foundation for Science & AI Research, he focuses on building collaborations among leading scientists, AI researchers, institutions, and industry. He brings a practical perspective on how AI-driven scientific ideas can attract support, cross institutional boundaries, and become real-world innovations.

Lu Chen

Lu Chen

Stanford University
Panelist

Lu Chen is a professor of neurosurgery and of psychiatry and behavioral sciences at Stanford University and a member of the Wu Tsai Neurosciences Institute. Her research investigates the cellular and molecular mechanisms governing synaptic function and plasticity in the developing and mature brain. A major focus of her work is homeostatic synaptic plasticity, including how local protein synthesis and retinoic-acid signaling regulate synaptic strength and contribute to neurodevelopmental disorders such as Fragile X syndrome.

Dongjin Song

Dongjin Song

University of Connecticut
Moderator

Dongjin Song is an associate professor in the School of Computing at the University of Connecticut. His research develops foundational AI and machine-learning methods for time-series analysis, graph-structured data, and continuously evolving systems. His work spans foundation models, large language models, multimodal and agentic AI, continual learning, and domain generalization, with an emphasis on trustworthy and interpretable decision-making in healthcare, biomedicine, environmental science, and other complex real-world applications.

Interactive panel

Where does discoverative AI go next?

Moderated by Dongjin Song and Dong Song, this audience-facing conversation invites attendees to ask questions, interact directly with panelists, and explore open challenges, future directions, and opportunities for collaboration.

Moderators
Dongjin Song + Dong Song
UConn + USC
Format
Audience-led Q&A
Questions and dialogue encouraged
Panel
Five invited experts
Neuroscience, AI, strategy, and translation
Program

Tentative workshop schedule

Invited presentations, audience Q&A, and a closing panel bringing together AI and neuroscience communities.

Tentative program: Friday, November 6, 2026 (Day 2). Session times are confirmed; speaker order and the final program may change. Room assignment to be announced.
10:10 AM
Welcome and workshop framingDong Song and Dongjin Song
Organizers
10:15 AM
Invited Speaker - Dong Song30-minute talk + 5-minute Q&A
Invited talk
10:50 AM
Invited Speaker - Shaul Druckmann30-minute talk + 5-minute Q&A
Invited talk
11:25 AM
Invited Speaker - Joseph Monaco30-minute talk + 5-minute Q&A
Invited talk
12:00 PM
Transition to lunch
Break
2:00 PM
Invited Speaker - Wei Wang30-minute talk + 5-minute Q&A
Invited talk
2:35 PM
Interactive panel discussionAudience Q&A with Charles Ng, Joseph Monaco, Lu Chen, Shaul Druckmann, and Wei Wang
Panel
3:20 PM
Closing remarks and next steps
Organizers
Participation

Join the conversation

Join for an in-person discussion of discoverative AI for understanding the brain.

  • Who should attend. Researchers and practitioners working across AI, neuroscience, biomedical engineering, cognitive science, and related fields.
  • Program. Invited talks, audience Q&A, and a closing panel.
  • Registration. Register through the official AIAS+ 2026 portal. There is no separate workshop registration or paper submission process.
Organizing team

Organizers

Advisory committee

Advisory Committee

Domain experts supporting the workshop across machine learning, data mining, and neural engineering.

Dr. Wei Cheng
NEC Labs America
Dr. Derek Aguiar
University of Connecticut
Dr. Yaguang Li
Google Brain
Dr. Zhengping Che
Midea
Dr. Sungyong Seo
Google Cloud AI
Dr. Chen Luo
Amazon A9
Dr. Abhishek Mukherji
Accenture Inc.
Dr. Xingjian Shi
HKUST
Dr. Jiayu Zhou
Michigan State University
Dr. Jilin Hu
Aalborg University
Dr. Fernando Gama
Morgan Stanley
Dr. Wei Zhu
Amazon
Dr. An Wang
Case Western Reserve University
Registration

Join us in San Francisco

All participants register through the official AIAS+ 2026 portal.

https://www.aiasplus.org
Register at aiasplus.org

Workshop registration is handled entirely through the AIAS+ 2026 Symposium — there is no separate registration system for this workshop.